TLI measurement is primarily used for the diagnosis of exocrine pancreatic insufficiency. This disease involves the portion of the pancreas that produces digestive enzymes. Insufficient enzyme production results in improper digestion of fats, carbohydrates, and proteins. The clinical signs shown by the patient include the production of large volumes of fatty feces and weight loss.
A single fasting blood sample is sent to a veterinary referral laboratory for trypsin-like immunoreactivity determination.